GroupWise 2012 not receiving mail

This is a strange error!!! I updated my OES server Sunday with the latest patches, everything seemed to be running fine after the system rebooted.  I found out this morning the users were unable to send mail to Internet addresses, even though everyone was receiving mail. To explain the system in is a GroupWise 2012 running  on an OES2 SP3, SLES10 SP4 Linux box, with GWAVA for mail security.  I checked the system and it looked like everything should be working.  So I stared by restarting the GroupWise and GWAVA servers, this resulted in no changes to the issues. Checking the web tools showed the post office and gateways were open.  I check the GroupWise monitor and it showed the MTA was unknown and GWIA wasn’t running,  which was counter  to all the other data and the logs showed no errors. After tracking the unsent messages, I finally found them waiting in the post office send Que.  So that told me that the POA and the MTA where not communicating for outbound, which did not make sense since it was receiving inbound mail.   I disabled the SSL thing that was could be causing a problem, no effect. So finally I changed the port of the MTA from 7100 to 7105 After restarting the GroupWise system, mail started to flow outbound. Netstat showed about 15 connection on port 7100 and only two on port 7105. Now the question is what caused this issue. The fix is a band-aid to get the system back in production, but it looks like a long weekend of trouble shooting to figure out what is actually is causing the problem.  The thing is  I did this on another server and it worked fine. Any thoughts?